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The al-Qaida-linked Islamic State of Iraq and Syria (ISIS) has played a key role in the war against Syria's government but now faces a major onslaught from other rebel forces. ISIS militants are also under fire in neighboring Iraq. NPR's Scott Simon and correspondent Deb Amos discuss how ISIS arose and what it wants to achieve.

On the 50th anniversary of President Lyndon Johnson's "War on Poverty" speech, the clash between Republicans and Democrats on how to alleviate poverty has come front and center. Republicans insist that anti-poverty programs have failed; Democrats say they have worked and should be expanded.

The Wall Street Journal reports the breach affected fewer than one million cards. The retailer has not released estimates on how many cards were compromised.

Berns was the star of a popular documentary on progeria, a disease that accelerates aging. His parents, spurred by Sam's own illness, were instrumental in the discovery of the first drug to treat the disease.

Tunisian lawmakers are poised to give final approval to a new constitution later this week. Political wrangling over the document has long delayed the ratification process, but if the constitution gains final approval on Tuesday, as planned, it will set the stage for a new round of parliamentary elections.

Four years ago, an earthquake heavily damaged Port-au-Prince and killed more than 200,000 people. Many areas of the Haitian capital now look much like they did before the 7.0-magnitude quake. But nearly 150,000 are still living in temporary structures.

The organization has unveiled its nominees for the 45th annual Image Awards, established to honor African-American performers who are often ignored by mainstream Hollywood. Some nominees are white, others of South-Asian or Latino heritage. NPR TV critic Eric Deggans wonders if that changes the meaning of the ceremony.

Secretary of State John Kerry is in Paris preparing for a long-delayed peace conference on Syria next week. He's urging the Syrian opposition to negotiate with a regime they've been trying to topple. The war in Syria has raged for three years and has befuddled the international community.

Full transcript of unedited interview with Morning Edition's Steve Inskeep.

There's evidence that many standard treatments for back pain — including surgery, spinal injections and painkillers — are often ineffective and can even worsen and prolong the problem.