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"We have to come together and take meaningful action to prevent more tragedies like this. Regardless of the politics," President Obama says in his weekly address.

In Who Could That Be at This Hour?, a prequel to A Series of Unfortunate Events, Daniel Handler satirizes pulp mysteries. Author and oenophile Paul Lukacs traces the 8,000-year history of wine. Also, David Edelstein reviews Zero Dark Thirty.

In the category of unintended consequences, Susan Rice's announcement about her future plans could mean a Republican in President Obama's inner circle, decorated Vietnam veterans overseeing the nation's military and foreign policy, and another special election for Senate in Massachusetts.

Saturday, police who are investigating gunman Adam Lanza in a deadly shooting in a Connecticut school announced they expected to piece together a picture the gunman's actions as well as his motives. Host Guy Raz speaks with NPR's Shankar Vedantam about how Lanza fits the profile of the mass shooter, and whether the recent tragedy can tell us how to avoid the next one.

LeVar Burton, host of the children's television show, Reading Rainbow, wrote a blog post Friday about how parents should speak to their kids in the aftermath of the latest school shooting. He joins host Guy Raz to discuss the importance of talking to kids and maintaining a normal routine.

As Congress once again heads for the brink in the "fiscal cliff" fight, a string of retiring senators noted the increased polarization sadly as they bid their colleagues farewell.

The outcome is unofficial at this point as the government has said it will not announce official results until the referendum concludes in the rest of Egypt next Saturday. Though voting counts differed, most major supporters and opponents of the constitution reported it had received a majority "yes" vote.

More details are emerging about the shooter and his victims in the worst act of deadly violence at an elementary school in U.S. history.

An Orthodox Jew, the singer-songwriter ran into trouble trying to tour in support of a major-label release without performing on the sabbath or high holy days. That and slow sales nearly killed Clare's career, but it got a reboot from an unlikely benefactor: Microsoft.

The mass shooting at a Connecticut elementary school has revived calls for stricter gun laws. The debate is not unfamiliar, but the nature of the event may provide new impetus for action. Exactly what kind of action might make a difference is another story.